Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.69 |
| ▸ | HRH2 | P25021 | 5/20 | 0.50 |
| ▸ | HRH1 | P35367 | 5/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1978511 | 0.99 | HRH3 (0.68) | HRH3HRH2HRH1OPRM1OPRD1 | |
| SCHEMBL2025810 | 0.96 | HRH3 (0.65) | HRH3HRH2HRH1OPRM1OPRD1 | |
| SCHEMBL4620858 | 0.95 | HRH3 (0.69) | HRH3HRH2HRH1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL1979708 | 0.95 | HRH3 (0.64) | HRH3HRH2HRH1OPRM1OPRD1 | |
| SCHEMBL2026097 | 0.94 | HRH3 (0.61) | HRH3HRH2HRH1OPRM1OPRD1 | |
| SCHEMBL4455420 | 0.93 | HRH3 (0.66) | HRH3HRH2HRH1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL1980035 | 0.93 | HRH3 (0.60) | HRH3HRH2HRH1OPRM1OPRD1 | |
| Oxalic Acid SCHEMBL4506377 | 0.92 | HRH3 (0.65) | HRH3HRH2HRH1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL3824771 | 0.92 | HRH3 (0.65) | HRH3HRH2HRH1OPRM1OPRD1 | |
| SCHEMBL3826298 | 0.89 | HRH3 (0.62) | HRH3OPRM1OPRD1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332910-B1 | New derivatives of azabicyclo[3.2.0]hept-3-yl, method for preparing same and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2013-01-30 | — | — | EP | disclosed |
| EP-2332910-A1 | New derivatives of azabicyclo[3.2.0]hept-3-yl, method for preparing same and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2011-06-15 | — | — | EP | disclosed |