Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 17/20 | 0.44 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20273698 | 0.86 | GBA1 (0.44) | GBA1PDE5A | |
| SCHEMBL14475095 | 0.79 | GBA1 (0.47) | GBA1 | |
| SCHEMBL14475176 | 0.79 | GBA1 (0.46) | GBA1PDE5A | |
| SCHEMBL14475218 | 0.76 | ABCG2 (0.52) | GBA1 | |
| SCHEMBL14474516 | 0.76 | ABCG2 (0.52) | GBA1 | |
| SCHEMBL14475596 | 0.76 | ABCG2 (0.52) | GBA1 | |
| SCHEMBL16184658 | 0.70 | GBA1 (0.42) | GBA1 | |
| SCHEMBL14474167 | 0.70 | GBA1 (0.42) | GBA1 | |
| SCHEMBL16184520 | 0.69 | GBA1 (0.41) | GBA1 | |
| SCHEMBL20273732 | 0.69 | ABCG2 (0.51) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3056207-B1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMA CO LTD (JP) | 2018-06-20 | — | — | EP | disclosed |