Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.49 |
| ▸ | ESRRG | P62508 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14301546 | 1.00 | ELANE (0.60) | ELANESRD5A2SIRT1LMNATYR | |
| SCHEMBL24215587 | 1.00 | ELANE (0.60) | ELANESRD5A2SIRT1LMNATYR | |
| SCHEMBL18413773 | 1.00 | ELANE (0.60) | ELANESRD5A2SIRT1LMNATYR | |
| SCHEMBL20827662 | 0.95 | ELANE (0.55) | ELANESRD5A2SIRT1LMNATYR | |
| SCHEMBL19339948 | 0.93 | SRD5A2 (0.66) | ELANESRD5A2SIRT1LMNAMAPT | |
| SCHEMBL26999140 | 0.93 | SRD5A2 (0.66) | ELANESRD5A2SIRT1LMNAMAPT | |
| SCHEMBL5079225 | 0.92 | ELANE (0.53) | ELANESRD5A2SIRT1LMNATYR | |
| SCHEMBL19540525 | 0.91 | ELANE (0.51) | ELANESRD5A2SIRT1LMNATYR | |
| SCHEMBL26109085 | 0.91 | ELANE (0.51) | ELANESRD5A2SIRT1LMNATYR | |
| SCHEMBL18657324 | 0.90 | ELANE (0.50) | ELANESRD5A2SIRT1LMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493981-B1 | HIGH TEMPERATURE POLYMER BLENDS OF POLY(ARYL ETHER KETONE PHTHALAZINONE) | POLYMICS LTD (US) | 2018-06-20 | — | — | EP | disclosed |