Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18399562 | 1.00 | GAA (0.37) | GAAEPHX2KDM1ANFKB1NFKB2 | |
| SCHEMBL13421931 | 1.00 | GAA (0.37) | GAAEPHX2KDM1ANFKB1NFKB2 | |
| Hydrochloric Acid SCHEMBL28940490 | 0.99 | GAA (0.36) | GAAEPHX2KDM1ANFKB1NFKB2 | |
| SCHEMBL13737125 | 0.88 | SSTR1 (0.30) | — | |
| SCHEMBL13737127 | 0.88 | SSTR1 (0.30) | — | |
| SCHEMBL3215447 | 0.88 | SSTR1 (0.30) | — | |
| SCHEMBL3215441 | 0.88 | SSTR1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL18786571 | 0.86 | SSTR1 (0.30) | — | |
| SCHEMBL16526339 | 0.85 | GAA (0.34) | GAAEPHX2KDM1ANFKB1NFKB2 | |
| SCHEMBL16526372 | 0.85 | HDAC4 (0.39) | GAAEPHX2KDM1ANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066387-B2 | Salts of a Pim kinase inhibitor | INCYTE CORPORATION (US) | 2021-07-20 | — | — | US | disclosed |
| US-20190270725-A1 | SALTS OF A PIM KINASE INHIBITOR | INCYTE CORPORATION | 2019-09-05 | — | — | US | disclosed |
| US-20180170907-A1 | SALTS OF A PIM KINASE INHIBITOR | INCYTE CORPORATION | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190270725-A1 | SALTS OF A PIM KINASE INHIBITOR | PIM1, PIM3, PIM2 | GAA 3063/4885EPHX2 4771/4885KDM1A 634/4885 |
| US-20180170907-A1 | SALTS OF A PIM KINASE INHIBITOR | PIM1, PIM3, PIM2 | GAA 3063/4885EPHX2 4771/4885KDM1A 634/4885 |
| US-11066387-B2 | Salts of a Pim kinase inhibitor | PIM1, PIM3, PIM2 | GAA 3063/4885EPHX2 4771/4885KDM1A 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.