SCHEMBL20280840

SCHEMBL20280840

CCOC(=O)CC(=O)C[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
HTT P42858 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.45
CTSK P43235 6/20 0.44
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
CTSS P25774 3/20 0.43
CYP2D6 P10635 1/20 0.41
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20280675 1.00 CYP1A2 (0.56) CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2
SCHEMBL18059449 0.84 CYP1A2 (0.47) CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2
SCHEMBL17034685 0.84 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2
SCHEMBL2617389 0.83 CYP1A2 (0.68) CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2
SCHEMBL27581318 0.83 CYP1A2 (0.68) CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2
SCHEMBL7641486 0.83 CYP1A2 (0.68) CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2
SCHEMBL5623452 0.82 KLK7 (0.52) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL14456732 0.82 KLK7 (0.52) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL4772969 0.81 CA1 (0.55) CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2
SCHEMBL14777840 0.81 CYP1A2 (0.60) CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018107236-A1 NOVEL COMPOUNDS AS ANTI-MYCOBACTERIALS THE UNIVERSITY OF SYDNEY (AU) 2018-06-21 WO disclosed