Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MDM4 | O15151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5276812 | 0.89 | SLC17A5 (0.64) | SLC17A5MEN1KMT2AMDM4TP53 | |
| SCHEMBL5622852 | 0.89 | SLC17A5 (0.64) | SLC17A5MEN1KMT2AMDM4TP53 | |
| SCHEMBL5622471 | 0.89 | SLC17A5 (0.64) | SLC17A5MEN1KMT2AMDM4TP53 | |
| SCHEMBL14456737 | 0.86 | SLC17A5 (0.80) | SLC17A5MEN1KMT2AMDM4TP53 | |
| SCHEMBL5622589 | 0.86 | SLC17A5 (0.80) | SLC17A5MEN1KMT2AMDM4TP53 | |
| SCHEMBL29855217 | 0.81 | MDM4 (0.52) | SLC17A5MDM4TP53MDM2CASP3 | |
| SCHEMBL22444637 | 0.81 | MDM4 (0.52) | SLC17A5MDM4TP53MDM2CASP3 | |
| SCHEMBL17054258 | 0.81 | MDM4 (0.52) | SLC17A5MDM4TP53MDM2CASP3 | |
| SCHEMBL29557307 | 0.81 | MDM4 (0.52) | SLC17A5MDM4TP53MDM2CASP3 | |
| SCHEMBL5051765 | 0.80 | SLC17A5 (0.58) | SLC17A5MEN1KMT2AMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018107236-A1 | NOVEL COMPOUNDS AS ANTI-MYCOBACTERIALS | THE UNIVERSITY OF SYDNEY (AU) | 2018-06-21 | — | — | WO | disclosed |