Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 20/20 | 0.74 |
| ▸ | NCOR2 | Q9Y618 | 9/20 | 0.74 |
| ▸ | MELK | Q14680 | 1/20 | 0.72 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | BCL6B | Q8N143 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20284080 | 0.91 | BCL6 (0.78) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL24717331 | 0.88 | BCL6 (0.80) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267680 | 0.88 | BCL6 (0.74) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL24717536 | 0.88 | BCL6 (0.79) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267186 | 0.88 | BCL6 (0.79) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284551 | 0.88 | BCL6 (0.79) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284217 | 0.87 | BCL6 (0.73) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284211 | 0.87 | BCL6 (0.76) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284216 | 0.87 | BCL6 (0.84) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL21787688 | 0.87 | BCL6 (0.84) | BCL6NCOR2MELKCHRM4BCL6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018108704-A1 | NEW 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-06-21 | — | — | WO | disclosed |