Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.67 |
| ▸ | BRD2 | P25440 | 20/20 | 0.67 |
| ▸ | BRD3 | Q15059 | 19/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20271009 | 1.00 | BRD4 (0.67) | BRD4BRD2BRD3CYP3A4CYP2D6 | |
| SCHEMBL20288516 | 0.89 | BRD4 (0.69) | BRD4BRD2BRD3CYP3A4CYP2D6 | |
| SCHEMBL20288494 | 0.88 | BRD4 (0.68) | BRD4BRD2BRD3CYP3A4CYP2D6 | |
| SCHEMBL20288485 | 0.88 | BRD4 (0.68) | BRD4BRD2BRD3CYP3A4CYP2D6 | |
| SCHEMBL26487416 | 0.88 | BRD4 (0.63) | BRD4BRD2BRD3CYP3A4CYP2D6 | |
| SCHEMBL20288947 | 0.87 | BRD4 (0.62) | BRD4BRD2BRD3CYP3A4CYP2D6 | |
| SCHEMBL20270156 | 0.87 | BRD4 (0.62) | BRD4BRD2BRD3CYP3A4CYP2D6 | |
| SCHEMBL20269997 | 0.87 | BRD4 (0.73) | BRD4BRD2BRD3CYP3A4CYP2D6 | |
| SCHEMBL20289254 | 0.87 | BRD4 (0.73) | BRD4BRD2BRD3CYP3A4CYP2D6 | |
| SCHEMBL20270750 | 0.86 | BRD4 (0.63) | BRD4BRD2BRD3CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018111805-A1 | TETRAHYDROQUINOLINE-BASED BROMODOMAIN INHIBITORS | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2018-06-21 | — | — | WO | disclosed |