Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.85 |
| ▸ | BRD2 | P25440 | 4/20 | 0.84 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.84 |
| ▸ | BRDT | Q58F21 | 4/20 | 0.84 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | IL17A | Q16552 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23787087 | 0.92 | BRD4 (1.00) | BRD4BRD2BRD3BRDTABCB1 | |
| SCHEMBL20291077 | 0.92 | BRD4 (1.00) | BRD4BRD2BRD3BRDTABCB1 | |
| SCHEMBL20271946 | 0.92 | BRD4 (1.00) | BRD4BRD2BRD3BRDTABCB1 | |
| SCHEMBL23787098 | 0.91 | BRD4 (1.00) | BRD4BRD2BRD3BRDTABCB1 | |
| SCHEMBL20271950 | 0.91 | BRD4 (1.00) | BRD4BRD2BRD3BRDTABCB1 | |
| SCHEMBL23787097 | 0.91 | BRD4 (0.87) | BRD4BRD2BRD3BRDTABCB1 | |
| SCHEMBL23787105 | 0.91 | BRD4 (1.00) | BRD4BRD2BRD3BRDTABCB1 | |
| SCHEMBL20271529 | 0.91 | BRD4 (1.00) | BRD4BRD2BRD3BRDTABCB1 | |
| SCHEMBL20291073 | 0.91 | BRD4 (0.87) | BRD4BRD2BRD3BRDTABCB1 | |
| SCHEMBL23787096 | 0.88 | BRD4 (0.83) | BRD4BRD2BRD3BRDTABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018112037-A1 | INHIBITORS OF BROMODOMAIN-CONTAINING PROTEIN 4 (BRD4) | ZHOU JIA (US) | 2018-06-21 | — | — | WO | disclosed |