Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | FAP | Q12884 | 2/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20292198 | 1.00 | DPP4 (0.38) | DPP4DPP7FAPPREPDPP8 | |
| SCHEMBL16992449 | 0.88 | CHRM4 (0.49) | DPP4DPP7FAPPREPDPP8 | |
| SCHEMBL16992448 | 0.88 | CHRM4 (0.49) | DPP4DPP7FAPPREPDPP8 | |
| SCHEMBL20291977 | 0.86 | TSHR (0.40) | ALDH1A1CYP1A2CYP2D6CYP2C9USP2 | |
| SCHEMBL20292744 | 0.86 | CHRM4 (0.37) | CHRM4HRH3ALDH1A1CHRM1 | |
| SCHEMBL20292056 | 0.85 | CHRM4 (0.36) | CHRM4HRH3CHRM1 | |
| SCHEMBL20292227 | 0.85 | CHRM4 (0.36) | CHRM4HRH3CHRM1 | |
| SCHEMBL20292133 | 0.83 | CHRM4 (0.37) | CHRM4HRH3ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL16992590 | 0.83 | CHRM4 (0.37) | CHRM4HRH3CHRM1 | |
| SCHEMBL20291999 | 0.83 | CHRM4 (0.37) | CHRM4HRH3ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102568-B1 | BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS. | HEPTARES THERAPEUTICS LTD (GB) | 2018-06-27 | — | — | EP | claimed |