SCHEMBL20296017

SCHEMBL20296017

C[C@@]1(O)C=NCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20296312 1.00
Hydrochloric Acid SCHEMBL3316124 0.67
SCHEMBL9851570 0.59
SCHEMBL21938785 0.59
SCHEMBL17873075 0.59
SCHEMBL7562212 0.59
SCHEMBL977698 0.57
Hydrochloric Acid SCHEMBL25381913 0.57
SCHEMBL989793 0.57
SCHEMBL28551607 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787793-B2 Heterocyclic compounds as immunomodulators INCYTE CORPORATION (US) 2023-10-17 US disclosed
EP-3558985-B1 BENZOOXAZOLE DERIVATIVES AS IMMUNOMODULATORS INCYTE CORP (US) 2022-09-07 EP disclosed
US-20220194931-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORPORATION 2022-06-23 US disclosed
US-10800768-B2 Heterocyclic compounds as immunomodulators INCYTE CORPORATION (US) 2020-10-13 US disclosed
EP-3558985-A1 BENZOOXAZOLE DERIVATIVES AS IMMUNOMODULATORS Incyte Corporation (US) 2019-10-30 EP disclosed
US-20190225601-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORPORATION 2019-07-25 US disclosed
US-10308644-B2 Heterocyclic compounds as immunomodulators INCYTE CORPORATION (US) 2019-06-04 US disclosed
US-20180179197-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORPORATION 2018-06-28 US disclosed
WO-2018119266-A1 BENZOOXAZOLE DERIVATIVES AS IMMUNOMODULATORS INCYTE CORPORATION (US) 2018-06-28 WO disclosed