⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256435 | 0.79 | — | — | |
| SCHEMBL30173730 | 0.76 | — | — | |
| SCHEMBL411434 | 0.74 | — | — | |
| SCHEMBL1643329 | 0.69 | — | — | |
| SCHEMBL10944192 | 0.67 | TSHR (0.40) | — | |
| SCHEMBL12119379 | 0.67 | — | — | |
| SCHEMBL9074612 | 0.67 | — | — | |
| SCHEMBL6686 | 0.65 | — | — | |
| SCHEMBL1645119 | 0.64 | — | — | |
| SCHEMBL204032 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350144-B1 | PROCATALYST COMPOSITION INCLUDING SILYL ESTER INTERNAL DONOR AND METHOD | GRACE W R & CO (US) | 2015-07-15 | — | — | EP | disclosed |
| EP-2350144-B1 | PROCATALYST COMPOSITION INCLUDING SILYL ESTER INTERNAL DONOR AND METHOD | GRACE W R & CO (US) | 2015-07-15 | — | — | EP | disclosed |
| US-8088872-B2 | Procatalyst composition including silyl ester internal donor and method | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-8088872-B2 | Procatalyst composition including silyl ester internal donor and method | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100130709-A1 | Procatalyst Composition Including Silyl Ester Internal Donor and Method | W. R. GRACE & CO.-CONN. | 2010-05-27 | — | — | US | disclosed |
| US-20100130709-A1 | Procatalyst Composition Including Silyl Ester Internal Donor and Method | W. R. GRACE & CO.-CONN. | 2010-05-27 | — | — | US | disclosed |