Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13834740 | 0.86 | BRD4 (0.48) | BRD4BTKPTGER4 | |
| SCHEMBL2029083 | 0.86 | BRD4 (0.48) | BRD4BTKPTGER4 | |
| SCHEMBL13834447 | 0.86 | BRD4 (0.62) | BRD4BTKPTGER4 | |
| SCHEMBL12632192 | 0.86 | BRD4 (0.62) | BRD4BTKPTGER4 | |
| SCHEMBL12764531 | 0.86 | BRD4 (0.52) | BRD4BTKPTGER4 | |
| SCHEMBL13835024 | 0.85 | BRD4 (0.50) | BRD4BTKPTGER4 | |
| SCHEMBL13835022 | 0.85 | BRD4 (0.50) | BRD4BTKPTGER4 | |
| SCHEMBL13834739 | 0.84 | BRD4 (0.51) | BRD4BTKPTGER4 | |
| SCHEMBL12630671 | 0.84 | BRD4 (0.51) | BRD4BTKPTGER4 | |
| SCHEMBL2035437 | 0.84 | BRD4 (0.50) | BRD4BRD2EP300BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011066211-A1 | AZABENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-06-03 | — | — | WO | disclosed |