SCHEMBL2031045

SCHEMBL2031045

CC(C)C[C@H](N)[C@@H](O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.56
ANPEP P15144 2/20 0.53
DNPEP Q9ULA0 1/20 0.53
SLC1A3 P43003 3/20 0.48
SLC1A2 P43004 3/20 0.48
RNPEP Q9H4A4 1/20 0.44
LAP3 P28838 4/20 0.43
TSHR P16473 1/20 0.41
SLC1A1 P43005 2/20 0.41
TP53 P04637 1/20 0.39
CACNA2D1 P54289 2/20 0.39
ENPEP Q07075 2/20 0.39
CACNB3 P54284 1/20 0.39
CACNA1C Q13936 1/20 0.39
PGR P06401 1/20 0.39
ADRA1A P35348 1/20 0.39
HTR2B P41595 1/20 0.39
CACNA2D2 Q9NY47 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2029393 1.00 SLC7A5 (0.56) SLC7A5ANPEPDNPEPSLC1A3SLC1A2
SCHEMBL1247473 1.00 SLC7A5 (0.56) SLC7A5ANPEPDNPEPSLC1A3SLC1A2
SCHEMBL762515 1.00 SLC7A5 (0.56) SLC7A5ANPEPDNPEPSLC1A3SLC1A2
SCHEMBL2452941 1.00 SLC7A5 (0.56) SLC7A5ANPEPDNPEPSLC1A3SLC1A2
SCHEMBL2033220 1.00 SLC7A5 (0.56) SLC7A5ANPEPDNPEPSLC1A3SLC1A2
SCHEMBL2034368 1.00 SLC7A5 (0.56) SLC7A5ANPEPDNPEPSLC1A3SLC1A2
Hydrochloric Acid SCHEMBL9514577 0.98 SLC7A5 (0.54) SLC7A5ANPEPDNPEPSLC1A3SLC1A2
Hydrochloric Acid SCHEMBL737245 0.98 SLC7A5 (0.54) SLC7A5ANPEPDNPEPSLC1A3SLC1A2
Hydrochloric Acid SCHEMBL9514582 0.98 SLC7A5 (0.54) SLC7A5ANPEPDNPEPSLC1A3SLC1A2
Hydrochloric Acid SCHEMBL9370266 0.98 SLC7A5 (0.54) SLC7A5ANPEPDNPEPSLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10633630-B2 Acceleration of Mycobacterium growth ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) 2020-04-28 US disclosed
EP-3158053-B1 ACCELERATION OF MYCOBACTERIUM GROWTH ST GEORGES HOSPITAL MEDICAL SCHOOL (GB) 2019-03-13 EP disclosed
US-9707282-B2 Small cationic antimicrobial peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2017-07-18 US disclosed
US-20170121672-A1 ACCELERATION OF MYCOBACTERIUM GROWTH ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) 2017-05-04 US disclosed
EP-3158053-A1 ACCELERATION OF MYCOBACTERIUM GROWTH St. George's Hospital Medical School (GB) 2017-04-26 EP disclosed
WO-2015193688-A1 ACCELERATION OF MYCOBACTERIUM GROWTH ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) 2015-12-23 WO disclosed
US-20150315240-A1 SMALL CATIONIC ANTIMICROBIAL PEPTIDES THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2015-11-05 US disclosed
US-9017656-B2 Small cationic antimicrobial peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2015-04-28 US disclosed
EP-2061886-B1 Small cationic immunomodulatory peptides UNIV BRITISH COLUMBIA (CA) 2014-05-07 EP disclosed
US-20130266597-A1 Small Cationic Antimicrobial Peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2013-10-10 US disclosed
US-5166400-A Intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates PFIZER INC. (US) 1992-11-24 US disclosed
US-5166400-A Intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates PFIZER INC. (US) 1992-11-24 US disclosed
US-5135914-A Controlling hypertension, hyperaldosteronism, and congestive heart failure WARNER-LAMBERT COMPANY (US) 1992-08-04 US disclosed
US-5036155-A Process for isopropyl 3S-amino-2R-hydroxy-alkanoates PFIZER INC. (US) 1991-07-30 US disclosed
US-5036155-A Process for isopropyl 3S-amino-2R-hydroxy-alkanoates PFIZER INC. (US) 1991-07-30 US disclosed
US-4965372-A Process and intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates PFIZER INC. (US) 1990-10-23 US disclosed
US-4965372-A Process and intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates PFIZER INC. (US) 1990-10-23 US disclosed
EP-0379288-A1 Process and intermediates for isopropyl 3S-amino-2R-hydroxyalkanoates PFIZER INC. (US) 1990-07-25 EP disclosed
EP-0379288-A1 Process and intermediates for isopropyl 3S-amino-2R-hydroxyalkanoates PFIZER INC. (US) 1990-07-25 EP disclosed
WO-1989007610-A1 RENIN INHIBITORS CONTAINING alpha-HETEROATOM AMINO ACIDS WARNER-LAMBERT COMPANY (US) 1989-08-24 WO disclosed