SCHEMBL2031064

SCHEMBL2031064

O=C1NC(CF)CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21963992 1.00
SCHEMBL18360767 1.00
SCHEMBL2035483 0.84
SCHEMBL19692710 0.84
SCHEMBL14638692 0.79
SCHEMBL16985228 0.78
SCHEMBL23535429 0.77
SCHEMBL962003 0.77
SCHEMBL6189306 0.77
SCHEMBL2366618 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111909173-B Benzoxazepine oxazolidinone compounds and methods of use thereof 豪夫迈·罗氏有限公司 2025-03-04 CN disclosed
CN-112047960-B Benzoxazepine oxazolidinone compounds and methods of use thereof 豪夫迈·罗氏有限公司 2024-08-02 CN disclosed
CN-112062778-B Benzoxazepine oxazolidinone compounds and methods of use thereof 豪夫迈·罗氏有限公司 2024-04-19 CN disclosed
EP-3778607-B1 BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE HOFFMANN LA ROCHE (CH) 2023-08-30 EP disclosed
EP-4212536-A1 BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE F. Hoffmann-La Roche AG (CH) 2023-07-19 EP disclosed
CN-116265453-A Compounds as AR inhibitors and uses thereof 南京圣和药业股份有限公司 2023-06-20 CN disclosed
EP-3567045-B1 BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE HOFFMANN LA ROCHE (CH) 2022-01-12 EP disclosed
EP-3805231-A1 INHIBITOR CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) 2021-04-14 EP disclosed
EP-3778607-A1 BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE F. Hoffmann-La Roche AG (CH) 2021-02-17 EP disclosed
CN-112062778-A Benzoxazepine compounds and methods of use thereof 豪夫迈·罗氏有限公司 2020-12-11 CN disclosed
US-20150221987-A1 ELECTROLYTIC SOLUTION FOR NON-AQUEOUS SECONDARY BATTERY, AND NON-AQUEOUS ELECTROLYTIC SOLUTION SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2015-08-06 US disclosed
US-20150152093-A1 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH NOVARTIS AG (CH) 2015-06-04 US disclosed
WO-2014141104-A1 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH NOVARTIS AG (CH) 2014-09-18 WO disclosed
US-20140275083-A1 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH NOVARTIS AG (CH) 2014-09-18 US disclosed
EP-2485314-A1 Nonaqueous electrolytic solution and nonaqueous electrolyte secondary cell Mitsubishi Chemical Corporation (JP) 2012-08-08 EP disclosed
US-8178246-B2 Nonaqueous electrolyte solution, nonaqueous electrolyte secondary cell, and carbonate compounds MITSUBISHI CHEMICAL CORPORATION (JP) 2012-05-15 US disclosed
EP-2339684-A2 Nonaqueous electrolytic solution, nonaqueous electrolyte secondary cell, and carbonate compounds Mitsubishi Chemical Corporation (JP) 2011-06-29 EP disclosed
US-20090253048-A1 NONAQUEOUS ELECTROLYTE SOLUTION, NONAQUEOUS ELECTROLYTE SECONDARY CELL, AND CARBONATE COMPOUNDS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-08 US disclosed
CN-101218706-A Nonaqueous electrolyte solution, nonaqueous electrolyte secondary battery, and carbonate compound MITSUBISHI CHEM CORP (JP) 2008-07-09 CN disclosed
EP-1890357-A1 NONAQUEOUS ELECTROLYTE SOLUTION, NONAQUEOUS ELECTROLYTE SECONDARY BATTERY AND CARBONATE COMPOUND Mitsubishi Chemical Corporation (JP) 2008-02-20 EP disclosed