Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.66 |
| ▸ | FNTA | P49354 | 9/20 | 0.62 |
| ▸ | FNTB | P49356 | 7/20 | 0.62 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.62 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Geraniol SCHEMBL27629962 | 1.00 | MEN1 (0.68) | MEN1CYP3A4ALOX15KMT2AMAPT | |
| Geranylgeraniol SCHEMBL1366492 | 0.98 | MAPT (0.69) | MEN1CYP3A4ALOX15KMT2AMAPT | |
| Pyrophosphoric Acid SCHEMBL28008996 | 0.98 | MAPT (0.69) | MEN1CYP3A4ALOX15KMT2AMAPT | |
| Farnesol SCHEMBL4584214 | 0.98 | MAPT (0.69) | MEN1CYP3A4ALOX15KMT2AMAPT | |
| Squalene SCHEMBL2065916 | 0.89 | FNTA (0.71) | KMT2AFNTAFNTBPGGT1BGGPS1 | |
| Squalene SCHEMBL2065918 | 0.89 | FNTA (0.71) | KMT2AFNTAFNTBPGGT1BGGPS1 | |
| Geraniol SCHEMBL20481327 | 0.89 | KMT2A (0.79) | MEN1CYP3A4ALOX15KMT2AMAPT | |
| Geraniol SCHEMBL20481326 | 0.89 | KMT2A (0.79) | MEN1CYP3A4ALOX15KMT2AMAPT | |
| Geraniol SCHEMBL27699074 | 0.89 | KMT2A (0.79) | MEN1CYP3A4ALOX15KMT2AMAPT | |
| Farnesol SCHEMBL15808561 | 0.87 | KMT2A (0.80) | MEN1CYP3A4ALOX15KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108474009-B | Maltose-dependent degreddeterminants, maltose-responsive promoters, stabilized constructs and their use in the production of non-catabolic compounds | 阿迈瑞斯公司 | 2022-10-04 | — | — | CN | disclosed |
| US-10385375-B2 | Preparation of 7-dehydrocholesterol and/or the biosynthetic intermediates and/or secondary products thereof in transgenic organisms | NOVOZYMES A/S (DK) | 2019-08-20 | — | — | US | disclosed |
| US-20170198328-A1 | PREPARATION OF 7-DEHYDROCHOLESTEROL AND/OR THE BIOSYNTHETIC INTERMEDIATES AND/OR SECONDARY PRODUCTS THEREOF IN TRANSGENIC ORGANISMS | ORGANOBALANCE GMBH (DE) | 2017-07-13 | — | — | US | disclosed |
| US-20150353980-A1 | PREPARATION OF 7-DEHYDROCHOLESTEROL AND/OR THE BIOSYNTHETIC INTERMEDIATES AND/OR SECONDARY PRODUCTS THEREOF IN TRANSGENIC ORGANISMS | ORGANOBALANCE GMBH (DE) | 2015-12-10 | — | — | US | disclosed |
| US-20130210072-A1 | PREPARATION OF 7-DEHYDROCHOLESTEROL AND/OR THE BIOSYNTHETIC INTERMEDIATES AND/OR SECONDARY PRODUCTS THEREOF IN TRANSGENIC ORGANISMS | ORGANOBALANCE GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20110151509-A1 | PREPARATION OF 7-DEHYDROCHOLESTEROL AND/OR THE BIOSYNTHETIC INTERMEDIATES AND/OR SECONDARY PRODUCTS THEREOF IN TRANSGENIC ORGANISMS | ORGANOBALANCE GMBH (BE) | 2011-06-23 | — | — | US | disclosed |
| US-7608421-B2 | Method for the production of 7-dehydrocholesterol and/or the biosynthetic intermediate or subsequent products thereof in transgenic organisms | ORGANOBALANCE GMBH (DE) | 2009-10-27 | — | — | US | disclosed |
| US-7556937-B2 | By culturing genetically modified yeast organism; reduced Delta 22-desaturase activity and an increased HMG-CoA reductase activity | ORGANOBALANCE GMBH (DE) | 2009-07-07 | — | — | US | disclosed |
| CN-101443081-A | Water-in-oil emulsion compositions comprising sunscreen actives and silicone elastomers | PROCTER & GAMBLE (US) | 2009-05-27 | — | — | CN | disclosed |
| CN-101426503-A | Compositions and methods of treatment for inhibiting kinase and/or HMG-COA reductase | PHARMIX CORP (US) | 2009-05-06 | — | — | CN | disclosed |
| CN-101321561-A | Water in oil emulsion compositions containing siloxane elastomers | PROCTER & GAMBLE (US) | 2008-12-10 | — | — | CN | disclosed |
| US-20060269986-A1 | Method for producing ergosta-5,7-dienol and/or biosynthetic intermediate and/or secondary products thereof in transgenic organisms | ORGANOBALANCE GMBH (DE) | 2006-11-30 | — | — | US | disclosed |
| US-20060240508-A1 | Preparation of 7-dehydrocholesterol and/or the biosynthetic intermediates and/or secondary products thereof in transgenic organisms | Aktiengesellschaft, Basf (DE) | 2006-10-26 | — | — | US | disclosed |
| CN-1791380-A | Personal care products comprising active agents in a gel network | PROCTER & GAMBLE (US) | 2006-06-21 | — | — | CN | disclosed |
| US-20060088903-A1 | Method for the production of zymosterol and/or the biosynthetic intermediate and/or subsequent products thereof in transgenic organisms | LANG CHRISTINE | 2006-04-27 | — | — | US | disclosed |
| US-5457119-A | Hapalindole-type alkaloids as antitumor agents, fungicides | ELI LILLY AND COMPANY (US) | 1995-10-10 | — | — | US | disclosed |
| US-5366890-A | Alkaloids from cultures | ELI LILLY AND COMPANY (US) | 1994-11-22 | — | — | US | disclosed |
| US-5292650-A | Aerobic culture | ELI LILLY AND COMPANY (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0543516-A1 | Hapalindole alkaloids as antifungal and antitumor agents | ELI LILLY AND COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |