Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14815848 | 0.93 | MCHR1 (0.35) | SCN3AKDM4ECNR1L3MBTL1NR1H2 | |
| SCHEMBL15462425 | 0.93 | MCHR1 (0.35) | SCN3AKDM4ECNR1L3MBTL1NR1H2 | |
| SCHEMBL14816060 | 0.92 | SCN3A (0.37) | SCN3AKDM4ECNR1L3MBTL1HTR6 | |
| SCHEMBL15462540 | 0.92 | SCN3A (0.37) | SCN3AKDM4ECNR1L3MBTL1HTR6 | |
| SCHEMBL14815759 | 0.90 | KDM4E (0.43) | SCN3AKDM4ECNR1L3MBTL1GAA | |
| SCHEMBL14816159 | 0.90 | KDM4E (0.43) | SCN3AKDM4ECNR1L3MBTL1GAA | |
| SCHEMBL14816165 | 0.90 | KDM4E (0.43) | SCN3AKDM4ECNR1L3MBTL1GAA | |
| SCHEMBL14815957 | 0.90 | KDM4E (0.43) | SCN3AKDM4ECNR1L3MBTL1GAA | |
| SCHEMBL15462432 | 0.87 | GRM5 (0.38) | NR1H2NR1H3OPRM1OPRD1NAAA | |
| SCHEMBL14816018 | 0.87 | GRM5 (0.38) | NR1H2NR1H3OPRM1OPRD1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118101-A1 | T-TYPE CALCIUM CHANNEL MODULATORS AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2018-06-28 | — | — | WO | disclosed |