⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703676 | 0.72 | — | — | |
| SCHEMBL31199061 | 0.68 | — | — | |
| SCHEMBL3182138 | 0.68 | — | — | |
| SCHEMBL7746034 | 0.68 | — | — | |
| SCHEMBL1586116 | 0.68 | — | — | |
| SCHEMBL18019315 | 0.68 | — | — | |
| SCHEMBL9600797 | 0.67 | — | — | |
| SCHEMBL11568357 | 0.67 | CRBN (0.55) | — | |
| SCHEMBL3340184 | 0.65 | CRBN (0.39) | — | |
| Succinimide SCHEMBL3805994 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283610-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | BIOGEN MA INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| EP-3558394-B1 | TETRAAZABICYCLO-MACROCYCLE BASED MANGANESE CHELATE COMPOUNDS SUITABLE AS MRI IMAGING AGENTS | GE HEALTHCARE AS (NO) | 2020-06-03 | — | — | EP | disclosed |
| WO-2018115314-A1 | TETRAAZABICYCLO-MACROCYCLE BASED MANGANESE CHELATE COMPOUNDS SUITABLE AS MRI IMAGING AGENTS | GE HEALTHCARE AS (NO) | 2018-06-28 | — | — | WO | disclosed |