Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.48 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 5/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085072 | 0.78 | KCNH2 (0.50) | KCNH2PIK3CAPI4KBMAP4K4MINK1 | |
| SCHEMBL21497167 | 0.77 | KCNH2 (0.49) | KCNH2PIK3CAPI4KBMAP4K4MINK1 | |
| SCHEMBL25010664 | 0.76 | KCNH2 (0.47) | KCNH2PIK3CAPI4KBMAP4K4MINK1 | |
| SCHEMBL21071606 | 0.75 | ALOX5AP (0.46) | KCNH2PIK3CAPI4KBMAP4K4MINK1 | |
| SCHEMBL3786718 | 0.75 | CYP3A4 (0.40) | MAP4K4FEN1GLAPOLBGAA | |
| SCHEMBL23951820 | 0.73 | PIK3CA (0.53) | KCNH2PIK3CAPI4KBMAP4K4MINK1 | |
| SCHEMBL21497106 | 0.72 | KCNH2 (0.45) | KCNH2PIK3CAPI4KBMAP4K4MINK1 | |
| SCHEMBL17407893 | 0.71 | FEN1 (0.54) | KCNH2PIK3CAPI4KBMAP4K4MINK1 | |
| SCHEMBL20329375 | 0.70 | TSHR (0.41) | FEN1ALOX5APGLAPOLBGAA | |
| SCHEMBL21135415 | 0.70 | KCNH2 (0.41) | KCNH2PIK3CAPI4KBMAP4K4MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018114783-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-06-28 | — | — | WO | disclosed |