⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19725395 | 0.79 | — | — | |
| SCHEMBL16232786 | 0.77 | — | — | |
| SCHEMBL13227435 | 0.77 | — | — | |
| SCHEMBL16706483 | 0.77 | — | — | |
| SCHEMBL17531872 | 0.77 | — | — | |
| SCHEMBL24372028 | 0.77 | — | — | |
| SCHEMBL16691684 | 0.77 | — | — | |
| SCHEMBL16489109 | 0.77 | — | — | |
| SCHEMBL6201895 | 0.77 | — | — | |
| SCHEMBL13167827 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10010580-B2 | Insulin independence among patients with diabetes utilizing an optimized hamster Reg3 gamma peptide | LEVETAN CLARESA (US) | 2018-07-03 | — | — | US | disclosed |
| US-10010578-B2 | Insulin independence among patients with diabetes utilizing an optimized hamster Reg3 gamma peptide | LEVETAN CLARESA (US) | 2018-07-03 | — | — | US | disclosed |
| US-10010579-B2 | Insulin independence among patients with diabetes utilizing an optimized hamster Reg3 gamma peptide | LEVETAN CLARESA (US) | 2018-07-03 | — | — | US | disclosed |