SCHEMBL20340898

SCHEMBL20340898

CC(N)CC1C(=O)Nc2ccccc21

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 9/20 0.67
▸ TDO2 P48775 3/20 0.67
▸ GSK3B P49841 2/20 0.54
▸ MAPT P10636 3/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ GAA P10253 1/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ HTR7 P34969 1/20 0.43
▸ BRPF1 P55201 1/20 0.42
▸ CREBBP Q92793 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2983658 0.87 IDO1 (0.61) IDO1TDO2GSK3BMAPTKDM4E
SCHEMBL20340870 0.84 IDO1 (0.63) IDO1TDO2GSK3BMAPTKDM4E
SCHEMBL25762243 0.83 IDO1 (0.70) IDO1TDO2GSK3BMAPTKDM4E
SCHEMBL25762241 0.82 IDO1 (0.72) IDO1TDO2GSK3BMAPTKDM4E
SCHEMBL20340874 0.81 IDO1 (0.56) IDO1TDO2GSK3BMAPTKDM4E
SCHEMBL9120585 0.81 IDO1 (0.63) IDO1TDO2GSK3BMAPTKDM4E
SCHEMBL25564665 0.81 IDO1 (0.63) IDO1TDO2GSK3BMAPTKDM4E
SCHEMBL24740358 0.80 IDO1 (1.00) IDO1TDO2GSK3BMAPTKDM4E
SCHEMBL5528789 0.80 IDO1 (1.00) IDO1TDO2GSK3BMAPTKDM4E
SCHEMBL31265741 0.80 IDO1 (1.00) IDO1TDO2GSK3BMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10683335-B2 Freeze-dried preparation containing high-purity PTH and method for producing same ASAHI KASEI PHARMA CORPORATION (JP) 2020-06-16 — — US disclosed
US-10011643-B2 Freeze-dried preparation containing high-purity PTH and method for producing same ASAHI KASEI PHARMA CORPORATION (JP) 2018-07-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10011643-B2 Freeze-dried preparation containing high-purity PTH and method for producing same PTH1R, PTMS, VIP IDO1 4715/4885TDO2 4359/4885GSK3B 4286/4885
US-10683335-B2 Freeze-dried preparation containing high-purity PTH and method for producing same PTH1R, PTMS, VIP IDO1 4780/4885TDO2 4605/4885GSK3B 3696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback