Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.32 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28874094 | 0.95 | TSHR (0.43) | TSHRLPAR3LPAR1LPAR2THRB | |
| SCHEMBL28874092 | 0.95 | TSHR (0.46) | TSHRLPAR3LPAR1LPAR2THRB | |
| SCHEMBL28874076 | 0.89 | TSHR (0.41) | TSHRLPAR3LPAR1LPAR2THRB | |
| SCHEMBL14675853 | 0.89 | TSHR (0.43) | TSHRLPAR3LPAR1LPAR2THRB | |
| SCHEMBL2040421 | 0.88 | TSHR (0.47) | TSHRLPAR3LPAR1LPAR2THRB | |
| SCHEMBL28874078 | 0.88 | TSHR (0.41) | TSHRLPAR3LPAR1LPAR2THRB | |
| SCHEMBL2037549 | 0.87 | TSHR (0.44) | TSHRLPAR3LPAR1LPAR2THRB | |
| SCHEMBL2037326 | 0.86 | TSHR (0.43) | TSHRTHRB | |
| SCHEMBL28874073 | 0.84 | TSHR (0.40) | TSHRLPAR3LPAR1LPAR2THRB | |
| SCHEMBL3677974 | 0.84 | TSHR (0.42) | TSHRLPAR3LPAR1LPAR2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512416-A2 | COSMETIC TREATMENT METHOD INVOLVING A COMPOUND CAPABLE OF CONDENSING IN SITU | L'Oréal (FR) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011073279-A2 | COSMETIC TREATMENT METHOD INVOLVING A COMPOUND CAPABLE OF CONDENSING IN SITU | L'OREAL (FR) | 2011-06-23 | — | — | WO | disclosed |