Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CDC7 | O00311 | 10/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15411899 | 0.81 | HASPIN (0.50) | HASPINKMT2ACDC7CHEK1CCNT1 | |
| SCHEMBL12969522 | 0.81 | CDC7 (0.51) | HASPINKMT2ACDC7CHEK1CCNT1 | |
| SCHEMBL15411898 | 0.81 | HASPIN (0.50) | HASPINKMT2ACDC7CHEK1CCNT1 | |
| SCHEMBL15410717 | 0.81 | CDC7 (0.51) | HASPINKMT2ACDC7CHEK1CCNT1 | |
| SCHEMBL15410718 | 0.81 | CDC7 (0.51) | HASPINKMT2ACDC7CHEK1CCNT1 | |
| SCHEMBL12968797 | 0.81 | HASPIN (0.50) | HASPINKMT2ACDC7CHEK1CCNT1 | |
| SCHEMBL15410420 | 0.80 | CDC7 (0.53) | HASPINKMT2ACDC7CHEK1CCNT1 | |
| SCHEMBL12968685 | 0.80 | CDC7 (0.53) | HASPINKMT2ACDC7CHEK1CCNT1 | |
| SCHEMBL15410419 | 0.80 | CDC7 (0.53) | HASPINKMT2ACDC7CHEK1CCNT1 | |
| SCHEMBL15411867 | 0.79 | HASPIN (0.48) | HASPINKMT2ACDC7CHEK1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2692728-B1 | NOVEL FURANONE DERIVATIVE | CARNA BIOSCIENCES INC (JP) | 2018-07-04 | — | — | EP | disclosed |