Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18789864 | 0.87 | RECQL (0.56) | RECQLALDH1A1HTTKDM4ECYP1A2 | |
| SCHEMBL15043749 | 0.83 | RECQL (0.58) | RECQLALDH1A1HTTKDM4ECYP1A2 | |
| SCHEMBL15807121 | 0.74 | RECQL (0.76) | RECQLALDH1A1HTTKDM4ECYP1A2 | |
| SCHEMBL12776201 | 0.73 | RECQL (0.69) | RECQLALDH1A1HTTKDM4ECYP1A2 | |
| SCHEMBL13325681 | 0.73 | RECQL (0.68) | RECQLALDH1A1HTTKDM4ECYP1A2 | |
| SCHEMBL12844631 | 0.71 | RECQL (0.83) | RECQLALDH1A1HTTKDM4ECYP1A2 | |
| SCHEMBL16199688 | 0.70 | RECQL (0.59) | RECQLALDH1A1HTTKDM4ECYP1A2 | |
| SCHEMBL1464710 | 0.69 | RECQL (0.73) | RECQLALDH1A1HTTKDM4ECYP1A2 | |
| SCHEMBL4477888 | 0.69 | RECQL (0.73) | RECQLALDH1A1HTTKDM4ECYP1A2 | |
| SCHEMBL259219 | 0.69 | RECQL (0.73) | RECQLALDH1A1HTTKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145930-B1 | FUSED TRIAZOLE DERIVATIVES AS PHOSPHODIESTERASE 10A INHIBITORS | Celon Pharma Sa (PL) | 2018-07-04 | — | — | EP | disclosed |