Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 11/20 | 0.52 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2725433 | 0.89 | DHODH (0.64) | DHODHIMPDH2 | |
| SCHEMBL2725436 | 0.89 | DHODH (0.64) | DHODHIMPDH2 | |
| SCHEMBL20344431 | 0.80 | DHODH (0.41) | DHODHIMPDH2 | |
| SCHEMBL2727740 | 0.79 | DHODH (0.63) | DHODHIMPDH2 | |
| SCHEMBL2727737 | 0.79 | DHODH (0.63) | DHODHIMPDH2 | |
| SCHEMBL15375113 | 0.78 | DHODH (0.63) | DHODHIMPDH2 | |
| SCHEMBL2725002 | 0.77 | DHODH (0.59) | DHODHIMPDH2 | |
| SCHEMBL2724998 | 0.77 | DHODH (0.59) | DHODHIMPDH2 | |
| SCHEMBL2724970 | 0.76 | DHODH (0.70) | DHODHIMPDH2 | |
| SCHEMBL2724967 | 0.76 | DHODH (0.70) | DHODHIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857010-B1 | DIHYDROOROTIC ACID DEHYDROGENASE INHIBITOR | INST OF MITOCHONDRIA SCIENCE INC (JP) | 2018-07-04 | — | — | EP | disclosed |