Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 4/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22692407 | 0.89 | IDH1 (0.43) | IDH1BRD4CREBBPHDAC1HDAC8 | |
| SCHEMBL20344731 | 0.84 | BRD4 (0.41) | BRD4CREBBPHDAC1HDAC8HDAC6 | |
| SCHEMBL30803804 | 0.82 | BRD4 (0.41) | BRD4CREBBPHDAC1HDAC8HDAC6 | |
| SCHEMBL20344748 | 0.82 | BRD4 (0.41) | BRD4CREBBPHDAC1HDAC8HDAC6 | |
| SCHEMBL20344770 | 0.82 | BRD4 (0.41) | BRD4CREBBPHDAC1HDAC8HDAC6 | |
| SCHEMBL15298954 | 0.81 | BRD4 (0.44) | BRD4CREBBPHDAC1HDAC8HDAC6 | |
| SCHEMBL20344751 | 0.78 | BRD4 (0.41) | BRD4CREBBPHDAC1HDAC8HDAC6 | |
| SCHEMBL29424983 | 0.78 | BRD4 (0.42) | IDH1BRD4CREBBPHDAC1HDAC8 | |
| SCHEMBL20344747 | 0.78 | BRD4 (0.42) | BRD4CREBBPHDAC1HDAC8HDAC6 | |
| SCHEMBL20344739 | 0.78 | BRD4 (0.42) | IDH1BRD4CREBBPHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342766-A1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) | 2018-07-04 | — | — | EP | disclosed |