Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 16/20 | 0.56 |
| ▸ | MET | P08581 | 14/20 | 0.56 |
| ▸ | MERTK | Q12866 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18044588 | 0.86 | AXL (0.59) | AXLMETMERTKFLT3SRC | |
| SCHEMBL18044611 | 0.84 | AXL (0.57) | AXLMETMERTKFLT3SRC | |
| SCHEMBL16709459 | 0.84 | AXL (0.59) | AXLMETMERTKFLT3SRC | |
| SCHEMBL18044640 | 0.83 | AXL (0.54) | AXLMETMERTKFLT3SRC | |
| SCHEMBL16709405 | 0.83 | AXL (0.57) | AXLMETMERTKFLT3 | |
| SCHEMBL20344602 | 0.82 | AXL (0.57) | AXLMETMERTKFLT3 | |
| SCHEMBL18044626 | 0.82 | AXL (0.55) | AXLMETMERTKFLT3KDR | |
| Trifluoroacetic Acid SCHEMBL18044744 | 0.82 | AXL (0.57) | AXLMETMERTKFLT3SRC | |
| SCHEMBL18045166 | 0.81 | AXL (0.52) | AXLMETMERTKFLT3SRC | |
| SCHEMBL18045151 | 0.81 | AXL (0.55) | AXLMETMERTKFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067356-B1 | PYRROLO PYRIMIDINE DERIVATIVE | ONO PHARMACEUTICAL CO (JP) | 2018-07-04 | — | — | EP | disclosed |