Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 2/20 | 0.31 |
| ▸ | EDNRA | P25101 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20345599 | 1.00 | PDK2 (0.34) | PDK2CHEK1PIK3CACDK1CDK4 | |
| SCHEMBL20345614 | 0.92 | PDK2 (0.39) | PDK2CHEK1PIK3CACDK1CDK4 | |
| SCHEMBL20345617 | 0.88 | PDK2 (0.36) | PDK2CHEK1PIK3CACDK1CDK4 | |
| SCHEMBL20345596 | 0.88 | PDK2 (0.36) | PDK2CHEK1PIK3CACDK1CDK4 | |
| SCHEMBL16018569 | 0.84 | — | — | |
| SCHEMBL16018535 | 0.84 | — | — | |
| SCHEMBL16018531 | 0.84 | — | — | |
| SCHEMBL18025310 | 0.84 | — | — | |
| SCHEMBL16018513 | 0.84 | — | — | |
| SCHEMBL16018566 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180190945-A1 | FREQUENCY DEPENDENT LIGHT EMITTING DEVICES | UNIV WAKE FOREST (US) | 2018-07-05 | — | — | US | disclosed |