Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 13/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21571642 | 0.98 | PAICS (0.45) | PAICSPTGDRPOLBSMYD3 | |
| SCHEMBL20352151 | 0.93 | PAICS (0.42) | PAICSPTGDRPOLB | |
| SCHEMBL20352090 | 0.89 | PAICS (0.54) | PAICS | |
| SCHEMBL21571641 | 0.89 | PAICS (0.43) | PAICSPTGDRPOLB | |
| SCHEMBL20340329 | 0.88 | PAICS (0.45) | PAICSPOLB | |
| SCHEMBL20339064 | 0.87 | PAICS (0.39) | PAICSPTGDR | |
| SCHEMBL21571640 | 0.86 | PAICS (0.42) | PAICSPOLB | |
| SCHEMBL20339045 | 0.85 | PAICS (0.38) | PAICSPTGDR | |
| SCHEMBL21571666 | 0.85 | PAICS (0.41) | PAICSSMYD3 | |
| SCHEMBL20352066 | 0.85 | PAICS (0.45) | PAICS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122549-A1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2018-07-05 | — | — | WO | disclosed |