Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.41 |
| ▸ | PAICS | P22234 | 16/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24220469 | 0.77 | SMYD3 (0.41) | SMYD3PAICS | |
| SCHEMBL20339062 | 0.76 | PAICS (0.45) | SMYD3PAICS | |
| SCHEMBL21571669 | 0.75 | SMYD3 (0.44) | SMYD3PAICS | |
| SCHEMBL21571660 | 0.72 | PAICS (0.45) | SMYD3PAICS | |
| SCHEMBL20352177 | 0.68 | SMYD3 (0.33) | SMYD3 | |
| SCHEMBL20340330 | 0.67 | PAICS (0.45) | SMYD3PAICS | |
| SCHEMBL21571648 | 0.64 | PAICS (0.42) | PAICS | |
| SCHEMBL20352164 | 0.63 | PAICS (0.54) | PAICS | |
| SCHEMBL19710279 | 0.59 | SMYD3 (1.00) | SMYD3PAICS | |
| SCHEMBL20352035 | 0.59 | PAICS (0.67) | PAICS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122549-A1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2018-07-05 | — | — | WO | disclosed |