Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | GLP1R | P43220 | 8/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20353234 | 1.00 | EPHX2 (0.43) | EPHX2GLP1RFAAHCNR1CNR2 | |
| SCHEMBL30230095 | 1.00 | EPHX2 (0.43) | EPHX2GLP1RFAAHCNR1CNR2 | |
| SCHEMBL20353221 | 1.00 | EPHX2 (0.43) | EPHX2GLP1RFAAHCNR1CNR2 | |
| SCHEMBL30601897 | 1.00 | EPHX2 (0.43) | EPHX2GLP1RFAAHCNR1CNR2 | |
| SCHEMBL20353132 | 1.00 | EPHX2 (0.43) | EPHX2GLP1RFAAHCNR1CNR2 | |
| SCHEMBL24982646 | 1.00 | EPHX2 (0.43) | EPHX2GLP1RFAAHCNR1CNR2 | |
| SCHEMBL20353219 | 1.00 | EPHX2 (0.43) | EPHX2GLP1RFAAHCNR1CNR2 | |
| SCHEMBL22271542 | 0.88 | EPHX2 (0.47) | EPHX2GLP1RPRMT1KDM4EADRA1A | |
| SCHEMBL15773390 | 0.88 | EPHX2 (0.47) | EPHX2GLP1RPRMT1KDM4EADRA1A | |
| SCHEMBL29975232 | 0.88 | TSHR (0.43) | EPHX2GLP1RPRMT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562823-B1 | FUNCTIONALIZED NANOLUC INHIBITORS | PROMEGA CORP (US) | 2023-02-08 | — | — | EP | disclosed |
| WO-2018125992-A1 | FUNCTIONALIZED NANOLUC INHIBITORS | PROMEGA CORPORATION (US) | 2018-07-05 | — | — | WO | disclosed |