Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339548 | 0.85 | KDM4E (0.51) | POLBRAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29902945 | 0.85 | KDM4E (0.51) | POLBRAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29903006 | 0.75 | MAPK1 (0.51) | POLBRAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL20339581 | 0.75 | MAPK1 (0.51) | POLBRAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6462546 | 0.73 | HDAC3 (0.58) | POLBRAB9AHDAC3HDAC1LMNA | |
| SCHEMBL28180282 | 0.73 | HDAC1 (0.62) | RAB9AHDAC3HDAC1SMN1; SMN2AGTR1 | |
| SCHEMBL14829731 | 0.73 | MAPK8 (0.40) | MAPK8LMNAAGTR1 | |
| SCHEMBL15424907 | 0.71 | CDC7 (0.42) | RAB9AHDAC3MAPK8SMN1; SMN2ALDH1A1 | |
| SCHEMBL23831225 | 0.71 | GRIK1 (0.49) | POLBRAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL26803617 | 0.70 | MAPK8 (0.40) | MAPK8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125961-A1 | POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS | MITOBRIDGE, INC. (US) | 2018-07-05 | — | — | WO | disclosed |