Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13172621 | 0.82 | GAA (0.53) | GAAKDM4EKMT2AL3MBTL1HTT | |
| SCHEMBL13172679 | 0.82 | GAA (0.53) | GAAKDM4EKMT2AL3MBTL1HTT | |
| SCHEMBL272472 | 0.80 | GAA (0.51) | GAAKDM4EKMT2AL3MBTL1HTT | |
| SCHEMBL12352252 | 0.78 | GAA (0.50) | GAAKDM4ETSHRKMT2AL3MBTL1 | |
| SCHEMBL6036614 | 0.78 | GAA (0.50) | GAAKDM4EKMT2AL3MBTL1HTT | |
| SCHEMBL13917689 | 0.78 | GAA (0.50) | GAAKDM4EKMT2AL3MBTL1HTT | |
| Ethylene SCHEMBL4022004 | 0.77 | GAA (0.49) | GAAKDM4EKMT2AL3MBTL1HTT | |
| SCHEMBL27533995 | 0.77 | GAA (0.49) | GAAKDM4EKMT2AL3MBTL1HTT | |
| SCHEMBL16161415 | 0.77 | GAA (0.49) | GAAKDM4ETSHRKMT2AL3MBTL1 | |
| SCHEMBL12942559 | 0.76 | TSHR (0.68) | GAAKDM4ETSHRKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180187010-A1 | SILICON-CONTAINING RESIN COMPOSITION | TOKYO OHKA KOGYO CO., LTD. (JP) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180187010-A1 | SILICON-CONTAINING RESIN COMPOSITION | CROCC, SRI, SEM1 | GAA 1840/4885KDM4E 2724/4885TSHR 4701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.