⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20228042 | 0.79 | — | — | |
| SCHEMBL18731442 | 0.74 | — | — | |
| SCHEMBL25753343 | 0.74 | — | — | |
| SCHEMBL18583179 | 0.70 | — | — | |
| SCHEMBL15693854 | 0.69 | — | — | |
| SCHEMBL12119877 | 0.69 | — | — | |
| SCHEMBL17453993 | 0.67 | — | — | |
| SCHEMBL26381320 | 0.63 | — | — | |
| SCHEMBL26269043 | 0.63 | — | — | |
| SCHEMBL19069627 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125746-A1 | 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS | Frequency Therapeutics, Inc. (US) | 2018-07-05 | — | — | WO | disclosed |