Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 11/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18616062 | 1.00 | LRRK2 (0.59) | LRRK2PIK3CAAKT1MTORLNPEP | |
| Hydrochloric Acid SCHEMBL20357364 | 0.99 | LRRK2 (0.58) | LRRK2PIK3CAAKT1MTORLNPEP | |
| Hydrochloric Acid SCHEMBL20357362 | 0.99 | LRRK2 (0.58) | LRRK2PIK3CAAKT1MTORLNPEP | |
| SCHEMBL18615426 | 0.80 | HRH3 (0.48) | LRRK2PIK3CASYK | |
| SCHEMBL20357391 | 0.80 | HRH3 (0.48) | LRRK2PIK3CASYK | |
| Hydrochloric Acid SCHEMBL20357392 | 0.79 | HRH3 (0.47) | LRRK2PIK3CASYK | |
| Hydrochloric Acid SCHEMBL20357393 | 0.79 | HRH3 (0.47) | LRRK2PIK3CASYK | |
| SCHEMBL18615748 | 0.78 | CYP2C19 (0.58) | LRRK2SYK | |
| Hydrochloric Acid SCHEMBL20357289 | 0.77 | CYP2C19 (0.57) | LRRK2SYK | |
| Hydrochloric Acid SCHEMBL20357286 | 0.77 | CYP2C19 (0.57) | LRRK2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345893-B1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES (JP) | 2019-10-30 | — | — | EP | disclosed |
| EP-3345893-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |