Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21171925 | 0.88 | HTT (0.67) | HTTTGM2FOLH1KEAP1NFE2L2 | |
| SCHEMBL3694316 | 0.87 | HTT (0.88) | HTTTGM2PTGER4FOLH1KEAP1 | |
| SCHEMBL125577 | 0.87 | HTT (0.88) | HTTTGM2PTGER4FOLH1KEAP1 | |
| SCHEMBL3693087 | 0.87 | HTT (0.88) | HTTTGM2PTGER4FOLH1KEAP1 | |
| SCHEMBL4857273 | 0.87 | HTT (0.88) | HTTTGM2PTGER4FOLH1KEAP1 | |
| SCHEMBL3287016 | 0.87 | HTT (0.88) | HTTTGM2PTGER4FOLH1KEAP1 | |
| SCHEMBL2876850 | 0.87 | HTT (0.88) | HTTTGM2PTGER4FOLH1KEAP1 | |
| SCHEMBL4858734 | 0.87 | HTT (0.88) | HTTTGM2PTGER4FOLH1KEAP1 | |
| SCHEMBL2875581 | 0.87 | HTT (0.88) | HTTTGM2PTGER4FOLH1KEAP1 | |
| SCHEMBL8674198 | 0.87 | HTT (0.88) | HTTTGM2PTGER4FOLH1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018129203-A2 | METHOD FOR TEMPORAL AND TISSUE-SPECIFIC DRUG DELIVERY AND INDUCED NUCLEIC ACID RECOMBINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-07-12 | — | — | WO | disclosed |