Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.49 |
| ▸ | BRD4 | O60885 | 5/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.49 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834347 | 0.92 | STAT3 (0.58) | STAT3CRBNBRD4RIPK2MAP1LC3B | |
| SCHEMBL21709494 | 0.90 | STAT3 (0.58) | STAT3CRBNBRD4RIPK2MAP1LC3B | |
| SCHEMBL17821364 | 0.90 | STAT3 (0.59) | STAT3CRBNBRD4RIPK2MAP1LC3B | |
| SCHEMBL23765963 | 0.89 | STAT3 (0.56) | STAT3CRBNBRD4RIPK2MAP1LC3B | |
| SCHEMBL23766258 | 0.89 | STAT3 (0.56) | STAT3CRBNBRD4RIPK2MAP1LC3B | |
| SCHEMBL23037309 | 0.88 | STAT3 (0.57) | STAT3CRBNBRD4MAP1LC3BCSNK1A1 | |
| SCHEMBL25032419 | 0.87 | CRBN (0.55) | STAT3CRBNBRD4RIPK2MAP1LC3B | |
| SCHEMBL23772935 | 0.87 | STAT3 (0.57) | STAT3CRBNBRD4RIPK2MAP1LC3B | |
| SCHEMBL23772804 | 0.87 | STAT3 (0.57) | STAT3CRBNBRD4RIPK2MAP1LC3B | |
| SCHEMBL23772833 | 0.87 | STAT3 (0.57) | STAT3CRBNBRD4RIPK2MAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200048276-A9 | MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-02-13 | — | — | US | disclosed |
| US-10017520-B2 | Myc modulators and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048276-A9 | MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | STAT3 19/4885CRBN 263/4885BRD4 633/4885 |
| US-10017520-B2 | Myc modulators and uses thereof | MYC, MYCBP, MYCBP2 | STAT3 19/4885CRBN 263/4885BRD4 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.