Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615479 | 0.89 | EPHX2 (0.53) | EPHX2EPHX1KMT2AMEN1KDM4E | |
| SCHEMBL18615480 | 0.76 | MEN1 (0.66) | EPHX2EPHX1KMT2AMEN1KDM4E | |
| SCHEMBL18615487 | 0.74 | MAPK14 (0.49) | EPHX2EPHX1KMT2AMEN1KDM4E | |
| SCHEMBL20357277 | 0.71 | EPHX2 (0.45) | EPHX2 | |
| SCHEMBL18615501 | 0.71 | EPHX2 (0.45) | EPHX2 | |
| SCHEMBL20976434 | 0.70 | KMT2A (0.47) | EPHX2EPHX1KMT2AMEN1KDM4E | |
| SCHEMBL18615444 | 0.70 | KMT2A (0.47) | EPHX2EPHX1KMT2AMEN1KDM4E | |
| SCHEMBL21525417 | 0.70 | EPHX2 (0.54) | EPHX2EPHX1KMT2AMEN1NPC1 | |
| SCHEMBL20357379 | 0.69 | EPHX2 (0.42) | EPHX2KMT2AKDM4EALDH1A1 | |
| SCHEMBL18615650 | 0.69 | EPHX2 (0.42) | EPHX2KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345893-B1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES (JP) | 2019-10-30 | — | — | EP | disclosed |
| EP-3345893-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |