Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004179 | 0.84 | ALK (0.77) | ALK | |
| SCHEMBL10272274 | 0.81 | ALK (0.59) | ALK | |
| SCHEMBL20004495 | 0.81 | ALK (0.58) | ALK | |
| SCHEMBL896748 | 0.79 | ALK (0.59) | ALK | |
| SCHEMBL20004572 | 0.78 | ALK (0.69) | ALK | |
| SCHEMBL896771 | 0.78 | ALK (0.74) | ALK | |
| SCHEMBL897165 | 0.78 | ALK (0.62) | ALK | |
| SCHEMBL20004085 | 0.77 | ALK (0.54) | ALK | |
| SCHEMBL21443120 | 0.77 | ALK (0.65) | ALK | |
| SCHEMBL896675 | 0.76 | ALK (0.57) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613729-A1 | TETRACYCLIC COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-02-26 | — | — | EP | disclosed |
| EP-3345903-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2019-10-09 | — | — | EP | disclosed |
| EP-3345903-A1 | TETRACYCLIC COMPOUNDS | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-07-11 | — | — | EP | disclosed |