Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004778 | 0.91 | ALK (0.73) | ALK | |
| SCHEMBL897750 | 0.90 | ALK (0.79) | ALK | |
| SCHEMBL897596 | 0.90 | ALK (0.83) | ALK | |
| SCHEMBL7811289 | 0.90 | ALK (0.64) | ALK | |
| SCHEMBL17434484 | 0.89 | ALK (0.81) | ALK | |
| SCHEMBL898160 | 0.89 | ALK (0.75) | ALK | |
| SCHEMBL898430 | 0.88 | ALK (0.89) | ALK | |
| SCHEMBL897265 | 0.86 | ALK (0.83) | ALK | |
| SCHEMBL898197 | 0.86 | ALK (1.00) | ALK | |
| SCHEMBL898251 | 0.85 | ALK (0.79) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613729-A1 | TETRACYCLIC COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-02-26 | — | — | EP | disclosed |
| EP-3345903-A1 | TETRACYCLIC COMPOUNDS | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-07-11 | — | — | EP | disclosed |