Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20367764 | 1.00 | KCNJ1 (0.50) | KCNJ1 | |
| SCHEMBL15437371 | 0.88 | KCNJ1 (0.49) | KCNJ1 | |
| SCHEMBL15437373 | 0.88 | KCNJ1 (0.49) | KCNJ1 | |
| SCHEMBL16122217 | 0.88 | KCNJ1 (0.49) | KCNJ1 | |
| SCHEMBL16897442 | 0.86 | KCNJ1 (0.50) | KCNJ1 | |
| SCHEMBL16906434 | 0.86 | KCNJ1 (0.50) | KCNJ1 | |
| SCHEMBL16906537 | 0.86 | KCNJ1 (0.50) | KCNJ1 | |
| SCHEMBL15437296 | 0.82 | KCNJ1 (0.52) | KCNJ1 | |
| SCHEMBL17457220 | 0.80 | KCNJ1 (0.47) | KCNJ1 | |
| SCHEMBL15449860 | 0.80 | KCNJ1 (0.47) | KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092230-B1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME (US) | 2018-07-11 | — | — | EP | disclosed |