SCHEMBL20370514

SCHEMBL20370514

C=C(C)C(=O)N(C)CCCc1ccc(-c2ccc(-c3ccc(C4CCC(CCCCC)CC4)cc3)cc2F)cc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ RARB P10826 3/20 0.42
▸ RARA P10276 1/20 0.40
▸ RARG P13631 1/20 0.40
▸ SPHK1 Q9NYA1 6/20 0.39
▸ FFAR4 Q5NUL3 2/20 0.37
▸ CYP3A4 P08684 2/20 0.36
▸ CYP2C9 P11712 2/20 0.36
▸ APP P05067 2/20 0.35
▸ FASN P49327 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ P2RY14 Q15391 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19854630 1.00 RARB (0.42) RARBRARARARGSPHK1FFAR4
SCHEMBL19854622 0.96 RARB (0.41) RARBRARARARGSPHK1FFAR4
SCHEMBL19855103 0.93 RARB (0.41) RARBRARARARGSPHK1FFAR4
SCHEMBL19854036 0.91 SPHK1 (0.39) SPHK1FFAR4CYP2C9
SCHEMBL19854633 0.91 SPHK1 (0.39) SPHK1FFAR4CYP2C9
SCHEMBL19854631 0.91 CYP2C9 (0.38) RARBRARARARGSPHK1FFAR4
SCHEMBL19853898 0.90 SPHK1 (0.46) SPHK1CYP2C9
SCHEMBL19853907 0.90 SPHK1 (0.48) RARBSPHK1CYP2C9
SCHEMBL19854629 0.88 RARB (0.42) RARBRARARARGSPHK1FFAR4
SCHEMBL19854624 0.88 RARB (0.42) RARBRARARARGSPHK1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 RARB 1437/4885RARA 1599/4885RARG 598/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 RARB 1437/4885RARA 1599/4885RARG 598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback