Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23355529 | 0.90 | NPSR1 (0.59) | NPSR1ADORA2AADORA1SMN1; SMN2ALOX15 | |
| SCHEMBL3747154 | 0.87 | NPSR1 (0.59) | NPSR1ADORA2AADORA1SMN1; SMN2ALOX15 | |
| SCHEMBL28529109 | 0.82 | NPSR1 (0.59) | NPSR1ADORA2AADORA1SMN1; SMN2KMT2A | |
| SCHEMBL13464671 | 0.81 | NPSR1 (0.46) | NPSR1ADORA2AADORA1ALOX15KMT2A | |
| SCHEMBL486201 | 0.78 | CCR1 (0.55) | NPSR1ADORA2A | |
| SCHEMBL15926179 | 0.76 | NPSR1 (1.00) | NPSR1SMN1; SMN2ALOX15RAB9ANPC1 | |
| SCHEMBL14076725 | 0.76 | NPSR1 (0.50) | NPSR1ADORA2AADORA1 | |
| Acetic Acid SCHEMBL6984469 | 0.75 | NPSR1 (0.53) | NPSR1ADORA2AALOX15 | |
| SCHEMBL9644603 | 0.74 | NPSR1 (0.48) | NPSR1ADORA2AADORA1RAB9AP2RX7 | |
| SCHEMBL11576989 | 0.74 | NPSR1 (0.47) | NPSR1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511260-B1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | UNIV GIFU (JP) | 2015-07-29 | — | — | EP | disclosed |
| EP-2511260-B1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | UNIV GIFU (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-8633304-B2 | Oligonucleotide derivative comprising an aromatic compound | GIFU UNIVERSITY (JP) | 2014-01-21 | — | — | US | disclosed |
| US-8633304-B2 | Oligonucleotide derivative comprising an aromatic compound | GIFU UNIVERSITY (JP) | 2014-01-21 | — | — | US | disclosed |
| US-8633304-B2 | Oligonucleotide derivative comprising an aromatic compound | GIFU UNIVERSITY (JP) | 2014-01-21 | — | — | US | disclosed |
| EP-2511260-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | Gifu University (JP) | 2012-10-17 | — | — | EP | disclosed |
| EP-2511260-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | Gifu University (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-20120245341-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | GIFU UNIVERSITY (JP) | 2012-09-27 | — | — | US | disclosed |
| US-20120245341-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | GIFU UNIVERSITY (JP) | 2012-09-27 | — | — | US | disclosed |
| US-20120245341-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | GIFU UNIVERSITY (JP) | 2012-09-27 | — | — | US | disclosed |
| WO-2011071078-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | 国立大学法人岐阜大学 (JP) | 2011-06-16 | — | — | WO | disclosed |
| WO-2011071078-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | 国立大学法人岐阜大学 (JP) | 2011-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245341-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | NSUN2, SLCO2A1, ABCB7 | NPSR1 2541/4885ADORA2A 160/4885ADORA1 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.