Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 19/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20374511 | 0.85 | HRH4 (0.43) | HRH4HRH3HTR3A | |
| SCHEMBL20374521 | 0.84 | HRH4 (0.48) | HRH4HRH3HTR3A | |
| SCHEMBL20374416 | 0.83 | HRH4 (0.61) | HRH4HRH3 | |
| SCHEMBL20374518 | 0.81 | HRH4 (0.60) | HRH4HRH3HTR3A | |
| SCHEMBL20374602 | 0.81 | HRH4 (0.60) | HRH4HRH3HTR3A | |
| SCHEMBL20374615 | 0.80 | HRH4 (0.63) | HRH4HRH3HTR3A | |
| SCHEMBL20374423 | 0.78 | HRH4 (0.42) | HRH4HRH3HTR3A | |
| SCHEMBL20859329 | 0.76 | HRH4 (0.58) | HRH4HRH3HTR3A | |
| SCHEMBL14828803 | 0.74 | HRH4 (1.00) | HRH4HRH3HTR3A | |
| SCHEMBL20374412 | 0.73 | HRH4 (0.51) | HRH4HRH3HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760865-B1 | NOVEL HETEROCYCLIC DERIVATIVES AND THEIR USES | C&C RES LAB (KR) | 2018-07-11 | — | — | EP | disclosed |