Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643279 | 0.84 | BCHE (0.67) | HDAC6BCHEACHEKDM4ESMPD1 | |
| SCHEMBL11209828 | 0.84 | BCHE (0.67) | HDAC6BCHEACHEKDM4ESMPD1 | |
| SCHEMBL28722865 | 0.82 | CYP19A1 (0.70) | HDAC6KDM4EHTR6DNM1MEN1 | |
| SCHEMBL19324341 | 0.81 | HDAC6 (0.59) | HDAC6BCHEACHEKDM4ESMPD1 | |
| SCHEMBL17150144 | 0.81 | P2RX4 (0.57) | HDAC6BCHEACHEKDM4ESMPD1 | |
| Hydrochloric Acid SCHEMBL19896404 | 0.79 | KMT2A (0.49) | MAOBMAOABCHEACHEKDM4E | |
| SCHEMBL20961472 | 0.78 | HDAC6 (0.68) | HDAC6BCHEACHEKDM4ESMPD1 | |
| SCHEMBL18638857 | 0.77 | HDAC6 (0.51) | HDAC6BCHEACHEKDM4ESMPD1 | |
| SCHEMBL17150143 | 0.77 | SMPD1 (0.78) | HDAC6BCHEACHEKDM4ESMPD1 | |
| SCHEMBL9768532 | 0.76 | CYP1A2 (0.70) | HDAC6MAOBMAOAACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345597-A2 | PKC DELTA INHIBITORS FOR USE AS THERAPEUTICS | Faller & Williams Technology, LLC (US) | 2018-07-11 | — | — | EP | disclosed |