Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896300 | 0.74 | PDE10A (0.56) | PDE10A | |
| SCHEMBL7453496 | 0.71 | PDE10A (0.60) | PDE10A | |
| SCHEMBL2160309 | 0.71 | PDE10A (0.60) | PDE10A | |
| SCHEMBL2160065 | 0.70 | PDE10A (1.00) | PDE10A | |
| SCHEMBL19389797 | 0.70 | PDE10A (0.52) | PDE10A | |
| SCHEMBL15417217 | 0.69 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15417201 | 0.69 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2160041 | 0.68 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7574215 | 0.67 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15417278 | 0.65 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526098-B1 | NITROGEN-CONTAINING HETEROARYL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2018-07-11 | — | — | EP | disclosed |