Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20800942 | 0.90 | GLP1R (0.42) | GLP1RTLR2 | |
| SCHEMBL20800989 | 0.89 | GLP1R (0.41) | GLP1RTLR2 | |
| SCHEMBL20375520 | 0.87 | GLP1R (0.40) | GLP1RTLR2 | |
| SCHEMBL18715475 | 0.84 | GLP1R (0.48) | GLP1RTLR2 | |
| SCHEMBL21287290 | 0.83 | GLP1R (0.42) | GLP1RTLR2 | |
| SCHEMBL21287666 | 0.82 | GLP1R (0.41) | GLP1RTLR2 | |
| SCHEMBL24697694 | 0.81 | GLP1R (0.41) | GLP1RTLR2 | |
| SCHEMBL24697314 | 0.80 | GLP1R (0.40) | GLP1R | |
| SCHEMBL21393232 | 0.79 | GLP1R (0.40) | GLP1RTLR2 | |
| SCHEMBL20375678 | 0.77 | GLP1R (0.53) | GLP1RTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662427-B2 | Compositions and methods for inhibiting gene expression of LPA | Arrowhead Pharmaceuticals, Inc. (US) | 2020-05-26 | — | — | US | disclosed |
| US-20180195070-A1 | Compositions and Methods for Inhibiting Gene Expression of LPA | Arrowhead Pharmaceuticals, Inc. | 2018-07-12 | — | — | US | disclosed |