Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20377016 | 0.94 | GRM2 (0.66) | GRM2 | |
| SCHEMBL20377003 | 0.89 | GRM2 (0.61) | GRM2 | |
| SCHEMBL20391520 | 0.88 | GRM2 (0.66) | GRM2 | |
| SCHEMBL14248530 | 0.87 | GRM2 (0.66) | GRM2 | |
| SCHEMBL20377045 | 0.87 | GRM2 (0.58) | GRM2 | |
| SCHEMBL20376990 | 0.87 | GRM2 (0.62) | GRM2 | |
| SCHEMBL16243814 | 0.86 | GRM2 (0.57) | GRM2 | |
| SCHEMBL20377035 | 0.86 | GRM2 (0.57) | GRM2 | |
| SCHEMBL14317241 | 0.85 | GRM2 (0.64) | GRM2 | |
| SCHEMBL20376915 | 0.84 | GRM2 (0.57) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2721029-B1 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES | MERCK SHARP & DOHME (US) | 2018-07-18 | — | — | EP | claimed |