Tyrosine

Tyrosine

SCHEMBL20377367

CC(O)C(N)C(=O)O.NC(=O)CC(N)C(=O)O.NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.63
PTGS1 P23219 2/20 0.46
ALPI P09923 1/20 0.46
PKM P14618 1/20 0.46
XIAP P98170 1/20 0.46
TPH1 P17752 2/20 0.45
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44
EGFR P00533 1/20 0.44
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
ALOX15 P16050 1/20 0.44
HTR2A P28223 1/20 0.44
PTGS2 P35354 1/20 0.44
RECQL P46063 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TAAR1 Q96RJ0 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL3443100 0.96 SLC7A5 (0.58) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL28846971 0.95 SLC7A5 (0.57) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL9551454 0.93 SLC7A5 (0.55) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL29176063 0.92 SLC7A5 (0.53) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1443654 0.92 SLC7A5 (0.75) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1443661 0.92 SLC7A5 (0.75) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL27584006 0.91 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL16820324 0.89 SLC7A5 (0.71) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL3909629 0.89 SLC7A5 (0.50) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL3909625 0.89 SLC7A5 (0.50) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228573-A9 METHOD FOR PRODUCING FUSION PROTEIN OF SERUM ALBUMIN AND GROWTH HORMONE JCR PHARMACEUTICALS CO., LTD. (JP) 2024-07-11 US disclosed
EP-4374913-A2 NOVEL HUMAN SERUM ALBUMIN MUTANT JCR Pharmaceuticals Co., Ltd. (JP) 2024-05-29 EP disclosed
US-20240132566-A1 METHOD FOR PRODUCING FUSION PROTEIN OF SERUM ALBUMIN AND GROWTH HORMONE JCR PHARMACEUTICALS CO., LTD. (JP) 2024-04-25 US disclosed
EP-3845644-B1 NOVEL HUMAN SERUM ALBUMIN MUTANT JAPAN CHEM RES (JP) 2024-04-24 EP disclosed
CN-114591445-B Novel human serum albumin mutant JCR制药股份有限公司 2024-04-23 CN disclosed
CN-114728043-B Aqueous pharmaceutical composition containing fusion protein of serum albumin and growth hormone JCR制药股份有限公司 2024-04-16 CN disclosed
US-11634474-B2 Human serum albumin mutant JCR PHARMACEUTICALS CO., LTD. (JP) 2023-04-25 US disclosed
EP-4059512-A1 AQUEOUS PHARMACEUTICAL COMPOSITION CONTAINING FUSION PROTEIN OF SERUM ALBUMIN AND GROWTH HORMONE JCR Pharmaceuticals Co., Ltd. (JP) 2022-09-21 EP disclosed
EP-4047006-A1 METHOD FOR PRODUCING FUSION PROTEIN OF SERUM ALBUMIN AND GROWTH HORMONE JCR Pharmaceuticals Co., Ltd. (JP) 2022-08-24 EP disclosed
CN-114728043-A Aqueous pharmaceutical composition containing fusion protein of serum albumin and growth hormone JCR制药股份有限公司 2022-07-08 CN disclosed
CN-114591445-A Novel human serum albumin mutant JCR制药股份有限公司 2022-06-07 CN disclosed
CN-114555646-A Method for producing fusion protein of serum albumin and growth hormone JCR制药股份有限公司 2022-05-27 CN disclosed
CN-107949638-B Novel human serum albumin mutants JCR制药股份有限公司 2022-05-13 CN disclosed
EP-3845644-A1 NOVEL HUMAN SERUM ALBUMIN MUTANT JCR Pharmaceuticals Co., Ltd. (JP) 2021-07-07 EP disclosed
US-11046751-B2 Human serum albumin mutant JCR PHARMACEUTICALS CO., LTD. (JP) 2021-06-29 US disclosed
EP-3348635-B1 NOVEL HUMAN SERUM ALBUMIN MUTANT JAPAN CHEM RES (JP) 2021-02-17 EP disclosed
US-20200247872-A1 NOVEL HUMAN SERUM ALBUMIN MUTANT JAPAN CHEM RES (JP) 2020-08-06 US disclosed
US-10654912-B2 Human serum albumin mutant JCR PHARMACEUTICALS CO., LTD. (JP) 2020-05-19 US disclosed
US-20180244754-A1 NOVEL HUMAN SERUM ALBUMIN MUTANT JCR PHARMACEUTICALS CO., LTD. (JP) 2018-08-30 US disclosed
EP-3348635-A1 NOVEL HUMAN SERUM ALBUMIN MUTANT JCR Pharmaceuticals CO., LTD. (JP) 2018-07-18 EP disclosed