Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 19/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2053912 | 0.89 | PDE10A (0.57) | PDE10A | |
| SCHEMBL2041718 | 0.85 | PDE10A (0.47) | PDE10A | |
| SCHEMBL2040125 | 0.85 | PDE10A (0.61) | PDE10A | |
| SCHEMBL2038930 | 0.83 | PDE10A (0.45) | PDE10A | |
| SCHEMBL2044926 | 0.82 | PDE10A (0.59) | PDE10A | |
| SCHEMBL2041258 | 0.81 | PDE10A (0.54) | PDE10A | |
| SCHEMBL2040973 | 0.81 | PDE10A (0.57) | PDE10A | |
| SCHEMBL2040336 | 0.81 | PDE10A (0.47) | PDE10A | |
| SCHEMBL2037025 | 0.80 | PDE10A (0.51) | PDE10A | |
| SCHEMBL2043214 | 0.78 | PDE10A (0.50) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072695-A1 | PHENYLIMIDAZOLE DERIVATIVES COMPRISING AN ETHYNYLENE LINKER AS PDE10A ENZYME INHIBITORS | H. LUNDBECK A/S (DK) | 2011-06-23 | — | — | WO | claimed |